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Alternating Pressure Mattress

Alternating pressure mattresses don't just prevent bedsores – they're a lifeline for patients already suffering from Stage 1-4 pressure ulcers who need immediate relief and healing support.

Save 10% with code WELCOME10 (automatically applied on select models). Questions? Call 833-499-4450 or email support@medshopdirect.com for immediate assistance.

Hospital Beds Mattress

Bariatric Mattress

Low Air Loss

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The Protekt Aire 4000DX mattress system on a hospital bed base. The dark blue mattress is partially articulated (raised head section), clearly showing the raised side rails. The digital pump unit is attached to the foot of the bed.

An elderly woman resting comfortably on a hospital bed equipped with the Protekt Aire 4000DX low air loss and alternating pressure mattress system. The digital pump unit is visible, attached to the foot of the bed.

Low Air Loss Alternating Pressure Mattress System for Hospital Bed | Proactive Medical Protekt Aire 4000DX

Proactive

Only 1 left!

$469.00

$469.00 - $469.00

$469.00

$600.00

$600.00 - $600.00

$600.00

This is for you if... You need basic alternating pressure therapy and can't afford to wait - caregivers manually set pressure but it WORKS

Why pay more? You won't - unless heel ulcers ($28,000 treatment cost) and sitting complications concern you - then Domus Auto is your answer

Tags: Alternating Pressure, Low Air Loss, Budget Conscious

HCPCS Code: EO277

$469.00

$469.00 - $469.00

$469.00

$600.00

$600.00 - $600.00

$600.00

You save $131.00 (22%)

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$469.00

$469.00 - $469.00

$469.00

$600.00

$600.00 - $600.00

$600.00

You save $131.00 (22%)

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Woman resting on the Protekt Aire 4600DXAB alternating pressure air mattress with raised side bolsters, installed on a hospital bed in a patient room

Low Air Loss Alternating Pressure Mattress System with Air Bolsters for Hospital Bed | 80" Length | Proactive Protekt® Aire 4600DXAB

Proactive

Only 5 left!

$764.00

$764.00 - $764.00

$764.00

$764.00 - $764.00

Size: 36”x80”x8”/11"
Digital Fall Prevention System – Combines raised air bolsters with center cut-outs and advanced digital pump controls for comprehensive patient safety and therapeutic customization
Enhanced Digital Technology – Auto Compressor Sleep Technology with LED weight settings and 2-year warranty provides superior performance and extended equipment life
Dual Safety Protection – Cell-on-cell design with power failure protection plus fall prevention bolsters - addresses two major patient safety concerns in one system
Save Over > 10% For Bulk Orders - Call 833-499-4450 (Need Tax Exemption? Call Now)

$764.00

$764.00 - $764.00

$764.00

$764.00 - $764.00

Ships Next Day

$764.00

$764.00 - $764.00

$764.00

$764.00 - $764.00

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Woman resting comfortably on the Protekt Aire 6000AB alternating pressure air mattress with raised side bolsters, connected to the digital pump at the side of the bed

Low Air Loss Alternating Pressure Mattress System with Air Bolsters for Hospital Bed | 80" Length | Proactive Protekt® Aire 6000AB

Proactive

Only 5 left!

$993.00

$993.00 - $993.00

$993.00

$1,200.00

$1,200.00 - $1,200.00

$1,200.00

Size: 36”x80”x8”/11”
Ultimate Clinical Flexibility – Four customizable alternating cycles with fowler seat-inflate feature provide unmatched therapeutic control
Maximum Safety Protection – Combines 450 lb capacity, raised air bolsters, and cell-on-cell power failure protection - addresses multiple patient safety concerns simultaneously
Premium Digital Performance – Deluxe digital pump with triple alarm monitoring and max firm mode delivers professional-grade clinical precision and comprehensive patient safety
Save Over > 10% For Bulk Orders - Call 833-499-4450 (Need Tax Exemption? Call Now)

$993.00

$993.00 - $993.00

$993.00

$1,200.00

$1,200.00 - $1,200.00

$1,200.00

You save $207.00 (17%)

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$993.00

$993.00 - $993.00

$993.00

$1,200.00

$1,200.00 - $1,200.00

$1,200.00

You save $207.00 (17%)

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Smart Value

Wellell Domus Auto Medical Air Mattress with Quilted Cover - MedShop Direct

Medical Air Mattress – Apex Wellell Domus Auto Alternating Pressure System

Wellell

In stock

$1,180.00

$1,180.00 - $1,180.00

$1,180.00

$1,180.00 - $1,180.00

🥈 SMART VALUE: Domus Auto - $1,180

This is for you if... You want automated precision that eliminates setup guesswork - this automatically detects patient weight, provides Fowler Boost for sitting support, and includes heel relief for diabetic protection

Why pay $700 more than Protekt Aire 4000DX? Because automation prevents costly mistakes - manual settings often get wrong pressure levels that delay healing

Tags: Alternating Pressure, Low Air Loss, Essential Plus, Auto-Adjusting, Heel Relief

HCPCS Code: E0277

Auto-Adjusting Technology

Zero Setup Errors

Ultra-Quiet Operation

Visual/Audio Alarms

450 LB Weight Capacity

Cell-on-Cell Design

Seat Inflate Mode

$1,180.00

$1,180.00 - $1,180.00

$1,180.00

$1,180.00 - $1,180.00

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$1,180.00

$1,180.00 - $1,180.00

$1,180.00

$1,180.00 - $1,180.00

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PressureGuard Span-Care Convertible mattress with features listed on a white background

A 3D cutaway illustration of the PressureGuard SpanCare Convertible mattress shown in a raised, seated position. The internal layers include a green "Geo-Matt" foam topper, blue side bolsters, and internal air cylinders.

Alternating Pressure Mattress for Hospital Bed - Powered & Non-Powered | PressureGuard® Span-Care® Convertible

TransferMaster

Only 2 left!

$2,026.64 - $3,672.24

$2,026.64

$2,026.64 - $3,672.24

Note: This mattress is a special order with a lead time of 2 to 3 weeks. Please allow for additional delivery time.
Dual Mode: Powered or Non-Powered – Use without electricity for prevention, add control unit for Stage 1-4 treatment
Self-Adjusting Air Cylinders – Automatically provides correct immersion and envelopment for any patient
Alternating Pressure + Auto-Firm – Powered mode prevents ulcers with timed auto-firm for transfers and CPR
LifeSpan® Bleach-Resistant Cover – Polycarbonate-fortified coating withstands harsh disinfectants without breakdown
500 lb Capacity (Powered Mode) – Supports bariatric and standard patients with proven pressure management
Save Over > 10% For Bulk Orders - Call 833-499-4450 (Need Tax Exemption? Call Now)

$2,026.64 - $3,672.24

$2,026.64

$2,026.64 - $3,672.24

Ships Next Day

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$2,026.64

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Technical specifications for the PressureGuard APM2 Mattress, featuring safety edges, shear transfer zones, 350 lbs weight capacity, and 80x35x7 inch dimensions.

product cutaway of the PressureGuard APM2 mattress showing the internal air cylinder system. The mattress features a dark green top cover, a contoured foam safety bolster in light blue and cream, and large black air cylinders inside that provide alternating pressure therapy. The digital control unit is shown connected at the foot of the bed.

Alternating Pressure Mattress with Lateral Rotation for Pressure Ulcers | PressureGuard® APM2

TransferMaster

Only 5 left!

$2,736.00 - $4,930.00

$2,736.00

$2,736.00 - $4,930.00

Weight limit: 350 lbs
Note: This mattress is a special order, please allow up to 2 weeks for delivery
Two Therapies in One Mattress – Switch instantly between alternating pressure and lateral rotation modes
Treats Stage 1-4 Pressure Injuries – Aggressive treatment for existing ulcers and prevention
Personalized Therapy Placement – Center is optimized for solo sleepers using the full mattress while Right is tailored for the right-hand side of the bed for shared sleeping arrangements
Digital Control Unit – Low pressure alarm, power failure alarm, auto-firm mode, float mode
Save Over > 10% For Bulk Orders - Call 833-499-4450 (Need Tax Exemption? Call Now)

$2,736.00 - $4,930.00

$2,736.00

$2,736.00 - $4,930.00

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$2,736.00

$2,736.00 - $4,930.00

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Prius Lateral Alternating Pressure Mattress - Advanced Pressure Relief - MedShop Direct

Low Air Loss Lateral Rotation Mattress System - Advanced Turn Therapy | 36"x80"x8" - Prius Rhythm Turn

Prius Healthcare USA

Only 2 left!

$4,353.46

$4,353.46 - $4,353.46

$4,353.46

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$4,353.46

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$4,353.46

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$4,353.46

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$4,353.46

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Critical Care

Prius LAL Mattress - Alternating Pressure & Lateral Rotation System Duet - MedShop Direct

Auto Fowler Low Air Loss Alternating Pressure & Lateral Rotation Mattress System - 36"x80"x11" | Prius DUET

Prius Healthcare USA

Only 2 left!

$5,123.00

$5,123.00 - $5,123.00

$5,123.00

$5,123.00 - $5,123.00

This is for you if... Manual turning every 2 hours is impossible with your staffing OR your patient is developing pneumonia from immobility - this AUTO FOWLER DETECTION and lateral rotation saves lives

Why pay $3,400 more? Because pneumonia complications and staffing costs make this investment pay for itself - this protects everyone involved

Tags: Alternating Pressure, Low Air Loss, Lateral Turn, Ultimate Healing, Critical Care, Auto Fowler Detection

Lateral Rotation Technology

Auto Fowler Detection

Pneumonia Risk Reduction

700 LB Weight Capacity

5 Therapy Modes

Staff Labor Reduction

Critical Care Grade

Mattress weight: 39.6 lbs

$5,123.00

$5,123.00 - $5,123.00

$5,123.00

$5,123.00 - $5,123.00

Ships Next Day

$5,123.00

$5,123.00 - $5,123.00

$5,123.00

$5,123.00 - $5,123.00

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Alternating Pressure Mattress

Shop Alternating Pressure Mattresses for Sale Direct from Factory

Alternating pressure mattresses are designed to help prevent and manage pressure injuries by continuously redistributing pressure across the body. By cycling air through individual cells, these systems help improve circulation, reduce prolonged pressure on vulnerable areas, and support patient comfort during extended bed rest.

At MedShop Direct, you'll find medical-grade alternating pressure mattress systems from trusted manufacturers with factory-direct pricing and fast free shipping nationwide. Many models combine alternating pressure therapy with low air loss technology to provide both pressure redistribution and moisture management for enhanced skin protection.

Why Choose an Alternating Pressure Mattress?

Helps reduce prolonged pressure that can contribute to pressure injuries
Promotes circulation through alternating inflation and deflation cycles
Supports skin integrity with continuous pressure redistribution
Available with low air loss technology for moisture control
Options for home care, long-term care, and acute care environments
Models available for standard and bariatric patient needs

Choosing the Right Alternating Pressure System

Whether you're seeking an entry-level solution for home care or an advanced therapeutic surface for complex clinical needs, selecting the right system depends on patient risk level, mobility, weight capacity requirements, and caregiver preferences.

Basic Alternating Pressure Systems offer reliable pressure redistribution with manual controls and straightforward operation, making them a practical choice for many home care settings.

Auto-Adjusting Alternating Pressure Systems automatically respond to patient weight and positioning, helping simplify setup while maintaining consistent therapy.

Advanced Therapy Systems may include features such as lateral rotation, Auto Fowler detection, enhanced low air loss therapy, and bariatric weight capacities for patients with more complex care requirements.

Alternating Pressure vs. Low Air Loss Mattresses

While both technologies are designed to support pressure injury prevention and treatment, they serve different functions.

Alternating pressure mattresses actively inflate and deflate air cells to redistribute pressure and improve circulation. Low air loss mattresses continuously circulate air through the mattress surface to help manage heat and moisture.

Many advanced mattress systems combine alternating pressure and low air loss technologies to provide comprehensive pressure relief, moisture management, and patient comfort.

Related Products

For additional pressure relief and patient support solutions, explore our collection of Hospital Bed Mattresses. Patients requiring higher weight capacities may benefit from our Bariatric Mattresses, while our Hospital Beds provide compatible bed frames for alternating pressure mattress systems.

Frequently Asked Questions

What is the difference between Low Air Loss and Alternating Pressure?
Low air loss mattresses circulate air to control moisture and keep the skin dry, while alternating pressure mattresses actively inflate and deflate cells to redistribute pressure. Low air loss systems focus on moisture management and alternating pressure systems provide continuous pressure redistribution. A majority of the ones offered at MedShop combine both technologies for optimal care.

How do Alternating Pressure Mattresses help with existing bed sores?
Alternating pressure mattresses utilize air bladders throughout the mattress that constantly inflate and deflate. This continuous movement reduces, eliminates and helps treat bed sores by promoting blood flow and circulation. The cycling pressure prevents tissue breakdown and supports wound healing.

Are Alternating Pressure Mattresses covered by insurance?
Most alternating pressure mattresses qualify for Medicare coverage under HCPCS Code E0277. Medical documentation must include frequent changes in body position requirements, need for elevation more than 30 degrees, and medical conditions requiring specialized positioning. Contact your insurance provider to verify specific coverage requirements and pre-authorization needs.

Here for You Every Step of the Way

Choosing the right equipment is a significant decision, and you don't have to make it alone. Our team at MedShop Direct is dedicated to helping you find the best bed for your specific needs. If you have questions about compatibility or need a personalized recommendation, we are here to guide you. For expert advice on any of our mattresses, contact us at 833-499-4450 or support@medshopdirect.com.

Hospital Beds

Hospital Beds Mattresses

Patient Lifts

The experience was great

From the initial sale to the warranty, everything was handled smoothly and efficiently. I would recommend to anyone. Helpful and professional . From the initial sale to the warranty, everything was handled smoothly and efficiently. I would recommend to anyone. Helpful and professional . From the initial sale to the warranty, everything was handled smoothly and efficiently. I would recommend to anyone. Helpful and professional .

Ken

Very helpful and fast

Mary Anderson

Very helpful

Omar was very helpful great to work with very knowledgeable. Omar was very helpful great to work with very knowledgeable. Omar was very helpful great to work with very knowledgeable.

Marylin Rodgers

Outstanding Customer Support and IC333 Bed

The bed is exactly what we needed for my husband after a severe stroke. Omar provided excellent, professional and compassionate costumer support. He was very attentive and supportive and made sure our every need was taken care of. The bed is exactly what we needed for my husband after a severe stroke. Omar provided excellent, professional and compassionate costumer support. He was very... The bed is exactly what we needed for my husband after a severe stroke. Omar provided excellent, professional and compassionate costumer support. He was very attentive and supportive and made sure our every need was taken care of.

Beth

Amazing Customer Service

I needed a hospital bed for my husband to be able to return home after a severe stroke. I contacted three companies. Omar was the only person who got back to me. He was extremely supportive, compassionate and professional from our first conversation until the bed arrived. He went above and beyond every step of the way and understood how important having this bed was for my husband to be able to be at home. The bed is making his recovery easier for him.During what was a very stressful and demanding time, Omar’s support was such a blessing.I definitely would recommend the bed and am grateful for the customer support and service of this company. I needed a hospital bed for my husband to be able to return home after a severe stroke. I contacted three companies. Omar was the... I needed a hospital bed for my husband to be able to return home after a severe stroke. I contacted three companies. Omar was the only person who got back to me. He was extremely supportive, compassionate and professional from our first conversation until the bed arrived. He went above and beyond every step of the way and understood how important having this bed was for my husband to be able to be at home. The bed is making his recovery easier for him.During what was a very stressful and demanding time, Omar’s support was such a blessing.I definitely would recommend the bed and am grateful for the customer support and service of this company.

Elizabeth L Hudson

We received great service!

Omar recommended some mattresses for my mom's hospital bed. At 90, Mom wants comfort so she can sleep peacefully.Well I found the perfect mattress for Mom thanks to Omar's recommendations.Medshopdirect offers a variety of mattress options and sizes. I purchased Icare's IC30. What a great choice that was! Mom loves that it fits her bed better, has a nice thickness and gives her the support she wants. Plus Mom said it is so comfortable. I will buy again at Medshopdirect for their great selection, good pricing, friendly staff, ease of purchase, and timely delivery. Thanks again Omar! Omar recommended some mattresses for my mom's hospital bed. At 90, Mom wants comfort so she can sleep peacefully.Well I found the perfect mattress for... Omar recommended some mattresses for my mom's hospital bed. At 90, Mom wants comfort so she can sleep peacefully.Well I found the perfect mattress for Mom thanks to Omar's recommendations.Medshopdirect offers a variety of mattress options and sizes. I purchased Icare's IC30. What a great choice that was! Mom loves that it fits her bed better, has a nice thickness and gives her the support she wants. Plus Mom said it is so comfortable. I will buy again at Medshopdirect for their great selection, good pricing, friendly staff, ease of purchase, and timely delivery. Thanks again Omar!

Sandra

Omar at MedShop was extremely helpful

our bed arrived on time, and we felt comfortable doing business with MedShop! our bed arrived on time, and we felt comfortable doing business with MedShop! our bed arrived on time, and we felt comfortable doing business with MedShop!

Jace Barr

Omar went over and beyond to assist me with the purchase of my icare bed. I am in California and would recommend med shop direct for their ease of my purchase.

Omar went over and beyond to assist me! Omar went over and beyond to assist me! Omar went over and beyond to assist me!

Lakee Imbert

Excellent Resource For Home Hospital Beds/Mattresses

I got the exact mattress I needed at an excellent price.Fast delivery.Plus, the customer service was superb! I got the exact mattress I needed at an excellent price.Fast delivery.Plus, the customer service was superb! I got the exact mattress I needed at an excellent price.Fast delivery.Plus, the customer service was superb!

Gwenny

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